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Prohormone Steroid Powder 4-Androstenedione For Contraception CAS 63-05-8

Prohormone Steroid Powder 4-Androstenedione For Contraception CAS 63-05-8

Brand Name : JNJG
Model Number : 63-05-8
Certification : iso9001
Place of Origin : china
MOQ : Negotiable
Price : negotiation
Payment Terms : Western Union, L/C, D/P, MoneyGram
Supply Ability : 5000kg/year
Delivery Time : 3-5 work days
Packaging Details : 5g/foil bag
CAS : 63-05-8
MF : C19H26O2
MW : 286.41
Appearance : Near white crystalline powder
Loss on drying : 0.5%
Usage : used in small rheumatoid arthritis, diuretic, and a variety of contraceptive
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Prohormone Steroid Powder 4-Androstenedione For Contraception CAS 63-05-8

Quick Detail

Product Name



3,17-Dioxoandrost-4-Ene;delta-(sup4)-Androsten-3,17-dione;delta(Sup4)-Androstene-3,17-dione;delta4-androsten-3,17-dione;delta-4-androstenedione;SKF 2170;skf2170;4-AD












white crystalline powder

Melting Point

170-171 °C(lit.)

Boiling Point




Specific Rotation

+193°- +202 °

Loss on drying



It is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.


4-Androstenedione is the common precursor of male and female sex hormones. Some 4-Androstenedione is also secreted into the plasma, and may be converted in peripheral tissues to testosterone and estrogens.

4-Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion of dehydroepiandrosterone to 4-Androstenedione via the enzyme 3-β-hydroxysteroid dehydrogenase.

The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to 4-androstenedione directly by way of 17,20-lyase. Thus,17,20-lyase is required for the synthesis of 4-androstenedione, whether immediately or one step removed.

The production of adrenal 4-Androstenedione is governed by ACTH, whereas production of gonadal 4-Androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total 4-androstenedione(about 3 mg/day). After menopause, 4-androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, 4-androstenedione is the principal steroid produced by the postmenopausal ovary.

An 4-Androstenediones Level May Be Used To

Evaluate adrenal gland function and to distinguish between androgen-secreting conditions that are caused by the adrenal glands from those that originate in the ovaries or testicles, if results of DHEAS and testosterone testing are abnormal.

Help diagnose tumors in the outer layer (cortex) of the adrenal gland or tumors outside of the adrenal gland that secrete ACTH (ectopic) and separate these conditions from ovarian or testicular tumors and cancers.

Diagnose congenital adrenal hyperplasia (CAH) and monitor CAH treatment, in addition to tests for testosterone and 17-hydroxyprogesterone, for example.

Help diagnose polycystic ovarian syndrome (PCOS) and help rule out other causes of infertility, no monthly menstrual periods (amenorrhea), and excess body and facial hair (hirsutism) in women who have abnormal results on tests for DHEAS, testosterone, and other hormones such as FSH, LH, prolactin, and estrogen.

Investigate and diagnose the cause of male physical characteristics (virilization) in young girls and early (precocious) puberty in young boys.

Help determine the cause of delayed puberty and investigate suspected ovarian or testicular failure.

How is 4-Androstenediones controlled?

Due to its secretion from a number of different glands and its often rapid conversion to other hormones, the control of 4-Androstenediones within the body is very complex. However, two key parts of the brain (the hypothalamus and pituitary gland) are known to be important in the control of 4-Androstenediones secretion from the testes, ovaries and adrenal cortex. The release of 4-Androstenediones by the adrenal cortex is thought to be related to the pituitary gland's secretion of a specialised hormone, adrenocor- ticotropic hormone. Precisely how adrenocorticotropic hormone and other hormones control the adrenal gland's production of 4-Androstenediones is, however, unclear. The testes and ovaries are stimulated to release 4-Androstenediones by luteinising hormone and follicle stimulating hormone. These are released from the anterior pituitary gland in response to a hormone signal from the hypothalamus.

What happens if I have too much 4-Androstenediones?

The effects of too much 4-Androstenediones are likely to result from its conversion in the body to oestrogen or testosterone.

In men, too much 4-Androstenediones may lead to an imbalance in oestrogen and testosterone production, leading to changes such as breast development. Depending on the cause of the excess 4-Androstenediones, other changes, such as the testes becoming smaller, might also occur.

In women, excess body and facial hair growth (called hirsutism), stopping of periods (amenorrhoea), worsening acne and changes to the genitalia may result from too much 4-Androstenediones.


1 High quality with competitive price:
(1) Standard: Enterprise Standard

(2) All Purity≥99%
(3) We are manufacturer and can provide high quality products with factory price.

2 Fast and safe delivery
(1) Parcel can be sent out in 24 hours after payment. Tracking number available
(2) Secure and discreet shipment. Various transportation methods for your choice.
(3) Customs pass rate ≥99%
(4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3 We have clients throughout the world.
(1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
(2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
(3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers

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